Thursday, November 24, 2011

New Breast Cancer Drug Boosts Survival

Peregrine Pharmaceuticals said breast cancer patients taking its experimental combination therapy lived seven months longer than patients who received standard chemotherapy in a mid-stage trial.

The company is testing its antibody drug bavituximab in combination with standard chemotherapy in patients with locally-advanced or metastatic breast cancer.

In the trial, patients receiving bavituximab combination therapy survived for an average of 23.2 months, compared with 16 months for patients receiving standard chemotherapy.

Bavituximab is an antibody designed to bind to a type of phosphatidylserine that becomes exposed in malignant or virally infected cells, triggering the body's immune system to attack the damaged cells.

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